Doctor-Recommended Microbiome Support for Your Baby

The first 1,000 days are critical to establishing a healthy immune system. Without it, children are at increased risk of developing immune-related conditions.

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I recommend infant-specific probiotics like Persephone’s synbiotic, which is designed to restore what nature intended every baby to have in those critical first months of life.

Dr. Tanya Altmann, MD

Mom, Pediatrician, Best-Selling Author

The only complete
probiotic for today’s
babies

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4

Keystone Strains

every baby needs to build a healthy foundation for life

HMO
prebiotic blend

to promote bacterial longevity in the gut

100%

daily recommended value of Vitamin D for infants

It is clear that the infant gut microbiome today in industrialized societies is different than in the past with loss of keystone, pioneer microbes. The good news is that this significant deficit is addressable.

Richard Insel, M.D.,

Pediatrician and Research Professor

Because little bodies deserve the highest standard.

We test more than required, more often than expected, and always with the same goal: to give you total peace of mind. Because when it comes to your baby’s health, nothing should be left to chance.

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Science-Backed

Developed by leading microbiome scientists and pediatricians (who are also parents).

Tailored for Babies

Uniquely built to replenish key beneficial microbes missing in nine out of ten babies today.**

Clean and Safe

3rd-party tested. Screened for heavy metal and major allergens. Clean Label Project Certified.

Clinically Validated

For safety and effectiveness in a randomized, double-blind placebo-controlled study*

Diapers and the discovery

We began with our My Baby Biome (MBB) Study, the largest and most diverse study ever done in the U.S. to map the infant gut microbiome.**

By analyzing over 400 dirty diapers from real families, we uncovered that 9 out of 10 babies are missing keystone strains of Bifodobacterium, critical microbes for immune development.

This was the foundation for everything that followed.

See the Publication

400+ diapers revealed that

90%

of U.S. babies are missing 1 or more keystone strains of Bifidobacterium

From poop to product

Redesigning health from the very beginning.

I've recommended Persephone to all the babies I take care of! Finally, a synbiotic that I am confident will be beneficial regardless of feeding method. The addition of HMOs, Vitamin D and strains of beneficial bacteria known to be deficient in all babies make it truly unique. My families report it's well tolerated, supports immunity and improves eczema even after short term use.

Dr. Tiffany Fischman

Sollis Health and Pacific Ocean Pediatrics

Stephanie Culler, PhD

CEO & Co-Founder, Microbiome Scientist & Mom

I'm Stephanie, a mom, scientist and founder

I had studied the microbiome for over a decade, but it wasn’t until I became a mom that I realized what was missing in our babies. 

Conversations with the leading pediatric experts and the results of our My Baby Biome study revealed a shocking global trend: most babies lack the gut microbes they need for lifelong health. 

I was shocked that no one had solved this problem.

So I am. This isn’t just my company, it’s my calling.

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Why Parents Choose Persephone

Made for Early Life

Persephone supports early-life health from the inside out. Trusted by parents and doctors, many families report improvements in digestion, sleep, fussiness, and overall comfort.

If you’re here through a doctor referral, your exclusive discount will be applied automatically at checkout.

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