
Her gut health
shapes her future
shapes her future
At Persephone, we use science and nature to create trusted products that help your baby grow up healthy. From day one and beyond.
What’s missing today matters tomorrow, and it’s a once-in-a-lifetime opportunity.
Our My Baby Biome study demonstrated that
9 out of 10
U.S babies are born without the essential levels of critical gut bacteria they need to build a thriving microbiome.
For generations, babies were born with a resilient gut microbiome, rich in protective bacteria that support immunity, digestion, and development.
Our study indicates that’s no longer the norm.
Without these critical bacteria, babies face a higher risk of:
Your baby deserves better bacteria
The fix for missing bacteria is probiotics. But most probiotics contain antiquated, white-label strains that are heavily manufactured. The world has changed, and those probiotics simply can’t do what needs to be done.

I had studied the microbiome for over a decade, but it wasn’t until I became a mom that I realized what was missing in our babies.
Conversations with the leading pediatric experts and the results of our My Baby Biome study revealed a shocking global trend: most babies lack the gut microbes they need for lifelong health.
I was shocked that no one had solved this problem.
So I am. This isn’t just my company, it’s my calling.
I created Persephone to bring today’s science to the families who need it most, starting in the gut. Every baby deserves the chance to thrive, as nature intended.

Dr. Stephanie Culler, PhD
CEO & Co-Founder, Scientist & Mom
Our Breakthrough
A first-of-its-kind combination of prebiotics & probiotics
Rewilding the gut isn’t a job for just any strain. We deployed cutting-edge science and thoughtful precision to restore what’s been lost. Our infant and toddler synbiotic is built for today’s world, not outdated assumptions.

Our strains are effective because they’ve evolved together
Proprietary
4 keystone strains designed to diversify your baby’s gut
Precise
Each probiotic strain is fed with the right prebiotics—like nature intended
Modern
Our innovative synbiotic is built on modern science and modern strains, not vintage bacteria
Born from Science. Trusted by Experts.
Persephone is backed by leading pediatricians, clinical researchers, and scientists who share a commitment to safer, more effective care.

At Persephone, exceptional clinical research leads to groundbreaking products.

Dr. Charles Baum, M.D.
Gastroenterologist and Lead Investigator of the Artemis Study
Persephone’s line of products is scientifically designed to support the rebalancing of children’s gut microbiome.

Dr. Alex LeBeaut, M.D.
Pediatrician and Leader in Pediatric Health Research
Persephone has developed a science-backed approach to addressing the gut dysbiosis in early infancy, which is quite common, as demonstrated recently in their published My Baby Biome study, and associated with risk of childhood diseases.

Dr. Dick Insel, M.D.
Pediatrician and Research Professor at University of Rochester School of Medicine & Dentistry

The first 1000 days establish your baby’s microbiome for life
Persephone isn’t just a supplement, it’s a stronger start in today’s world.
Sign up for expert insights, product information, and exclusive early access to our synbioitic.